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Name: Gardimax medica lemon
Form: lozenges
Dosage: 5mg+1mg
Package: 24 tablets (2 blist.po 12 szt.)
OTC medication
Drug for symptomatic use to relieve pain associated with inflammation or irritation in the course of inflammation of the mouth and throat.
1 Gardimax medica lemon l ozenge contains: 5 mg chlorohexidine dihydrochloride and 1 mg lidocaine hydrochloride.
Lidocaine hydrochloride is a topical anesthetic from the amide group with a surface anesthetic effect without interfering with the rate of conduction of nerve impulses at the site of application. Chlorhexidine exhibits antimicrobial activity by non-specific binding to the phospholipids of bacterial cell membranes. It inhibits dehydrogenase and ATP-ase activity within bacterial cell membranes and impairs permeability to potassium ions, nucleotides and amino acids. It has bacteriostatic and bactericidal effects especially on Gram-(+) bacteria, Candida albicans and weaker on Gram-(-) bacteria. Streptococcus mutans, Streptococcus salivarius, Escherichia coli, Selenomonas and anaerobic bacteria and Candida albicans yeasts are particularly sensitive to chlorhexidine. Less susceptible are strains of Streptococcus sanguis, Proteus, Pseudomonas, Klebsiella and Veillonella. Antibacterial activity depends on the concentration. At low concentrations below 20 mg/L, it shows mainly bacteriostatic activity, at higher concentrations it shows bactericidal activity.
Adults: 6-10 lozenges per day, suck slowly. Children aged 6 years and older: half the adult dose (3-5 lozenges per day). Drug for short-term symptomatic use: 3-4 days. If there is no improvement after this period, or if new complaints and/or general symptoms, such as fever, appear already during use, the patient should contact a doctor.
For use on the oral mucosa and intranasal administration.
Hypersensitivity to any active substance or other topical anesthetics of the amide group or to any of the excipients; use in children under 30 months of age.
This is a medication. For safety, use it according to the package insert. Do not exceed the maximum dose of the drug. If in doubt, consult your doctor or pharmacist.
Disinfectants do not sterilize; they temporarily reduce the number of microorganisms in the mouth and throat. Use of this product should be limited to cases when relief of existing pain and irritation is absolutely necessary. Gardimax medica lemon medicinal product should not be used for a long period of time. Do not use one dose after another. The use of the product should be avoided in people who are particularly prone to allergies. The product does not contain sugar, it can be used in diabetics. The product contains propylene glycol, which may cause alcohol-like symptoms. The drug has not been found to affect the ability to drive and operate mechanical devices in motion.
Due to possible interactions, antiseptics should be avoided. The combination of local anesthetics and cholinesterase inhibitors should be avoided. Lidocaine hydrochloride may increase the concentration of methemoglobin in the blood in patients concurrently receiving other drugs that affect its formation, such as sulfonamides. Cimetidine, β-blockers, norepinephrine, inhaled anesthetics inhibit lidocaine metabolism by decreasing hepatic flow, leading to an increase in serum drug concentrations. Barbiturates, rifampicin, phenytoin accelerate lidocaine metabolism through activation of liver microsomal enzymes. Lidocaine enhances the effects of drugs that relax striated muscles.
The drug product should not be used during pregnancy unless absolutely necessary. A decision should be made whether to discontinue nursing or continue the product. The benefits to the child of breastfeeding and the benefits to the woman of treatment with the product should be considered.
Immune system disorders: (rarely) allergic reactions involving the skin and mucous membranes (rash, oral mucositis, peeling of the oral mucosa, swelling of the salivary glands), anaphylactic reactions. Nervous system disorders: (unknown) taste disturbances. Gastrointestinal disorders: (unknown) burning sensation on the tongue, brown discoloration on the tongue, teeth after long-term use of chlorhexidine (these discolorations can be removed).
Due to the content of lidocaine, overdose symptoms affecting the CNS and cardiovascular system may occur. Restlessness, yawning, nervousness, tinnitus, nystagmus, muscle tremors, convulsions, depression, respiratory failure. Decrease in myocardial tone, peripheral vasodilation, hypotension, bradycardia, cardiac arrhythmia, cardiac arrest. Chlorhexidine is absorbed from the gastrointestinal tract to a very low degree. No suitable antidote is available. Management: symptomatic treatment.
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