Claritine Allergy 10 mg x 10 tablets (parallel import - Greece)

Claritine Allergy 10 mg 10 tablets

Parallel import Medezin

Name: Claritine Allergy
Form: tablets.
Dose: 0.01 g
Package: 10 tabl.

Claritine Allergy - description and indications

Indications for use:

Claritine Allergy medicinal product is indicated for the symptomatic treatment of allergic rhinosinusitis and chronic idiopathic urticaria.

Action

Loratadine, the active substance of the medicinal product, is a tricyclic antihistamine, a selective antagonist of peripheral histamine _H1 receptors. At recommended doses, loratadine does not exhibit central sedative or anticholinergic effects in most populations. In long-term studies, no clinically significant changes in vital laboratory or physical parameters or in electrocardiographic recordings were observed. Loratadine has no significant effect on_H2 receptors. It has no effect on the reuptake of norepinephrine and has virtually no effect on cardiovascular function or on the activity of the cardiac stimulatory system.

Composition - what ingredients are contained in the drug Claritine Allergy

One tablet of Claritine All ergy contains 10 mg of loratadine.

Dosage - how to use the drug Claritine Allergy

Adults and children over 12 years of age: 10 mg (1 tablet) once/day. Children and adolescents. Children aged 6-12 years: weight greater than 30 kg: 10 mg (1 tabl.) once/day. It is not advisable to use a tabl (10 mg) in children whose b.w. is less than 30 kg. Patients with hepatic impairment. In patients with severe hepatic insufficiency, a lower initial dose should be used, as the clearance of loratadine in these patients may be reduced. In such cases, adults and children with a weight greater than 30 kg should be given 10 mg of loratadine, every other day. Patients with renal impairment. No dose adjustment is necessary in patients with renal insufficiency. Elderly patients. There is no need to change the dose in elderly patients.

Notes

Claritine Allergy medicinal product can be taken regardless of meals.

Contraindications

Hypersensitivity to the active substance (loratadine) or to any of the excipients. Do not use the medicinal product during pregnancy.

Notes and warnings regarding the drug Claritine Allergy

This is a medication. For safety, use it according to the package insert. Do not exceed the maximum dose of the drug. If in doubt, consult your doctor or pharmacist.

Special warnings / Precautions

Caution should be exercised when using the medicinal product in patients with severe hepatic insufficiency. When using the medicinal product in syrup form in diabetic patients, take into account the fact that 1 ml of the product contains 0.6 g of sucrose. Patients with rare hereditary disorders related to fructose intolerance, glucose-galactose malabsorption syndrome or saccharase-isomaltase deficiency should not take this medicinal product. The medicinal product should be discontinued approximately 48 h before the scheduled allergic skin tests, as antihistamines may cause false-negative results of these tests (they may reduce or completely inhibit a skin reaction that would normally be positive). In clinical trials designed to assess driving ability, loratadine did not cause impairment. However, patients should be informed that in some individuals, very rarely, drowsiness occurred, which could interfere with the ability to drive and operate machinery.

Interactions

Claritine Allergy medicinal product administered concomitantly with alcohol does not potentiate its effects to an extent assessable by psychomotor tests. Potential interactions may occur with all known CYP3A4 or CYP2D6 inhibitors as a result of increased plasma concentrations of loratadine, which may result in increased side effects. In controlled clinical trials, concomitant use of loratadine with ketoconazole, erythromycin or cimetidine has been shown to increase plasma concentrations of loratadine, but without clinically significant changes.

Pregnancy and lactation

No teratogenic effects of loratadine have been demonstrated in animal studies. The safety of the product during pregnancy has not been established. Do not use the medicinal product during pregnancy. Loratadine passes into breast milk, so it is not recommended to take loratadine during breastfeeding.

Side effects

In clinical trials involving children 2-12 years, the following adverse reactions were observed compared to placebo: headache (2.7%), nervousness (2.3%) and fatigue (1%). In clinical trials with adult patients and adolescents, in the indication areas of allergic rhinosinusitis and chronic idiopathic urticaria, adverse reactions were observed in 2% of patients after the recommended dose of 10 mg/day. The most commonly observed adverse reactions, compared to placebo, included drowsiness (1.2%), headache (0.6%), increased appetite (0.5%) and insomnia (0.1%), as well as fatigue, dry mouth, nausea, gastritis and rash. Immune system disorders: anaphylaxis. Nervous system disorders: dizziness. Cardiac disorders: tachycardia, palpitations. Liver and biliary tract disorders: abnormal liver function. Skin and subcutaneous tissue disorders: alopecia.

Overdose

Overdose of loratadine causes an increase in cholinolytic symptoms. After an overdose of loratadine, the following have been observed: drowsiness, accelerated heart rate and headache. In case of overdose, symptomatic and maintenance treatment should be administered immediately, and continued for as long as necessary. Activated charcoal in the form of an aqueous suspension can be administered. Gastric lavage can be performed. Loratadine cannot be eliminated from the body by hemodialysis; it is not known whether it can be eliminated by peritoneal dialysis. After providing assistance, the patient should continue to be monitored.