Laremid 2 mg x 10 tabl.

How to use: Use as directed by your doctor
Detailed instructions for use can be found in the leaflet included in the package.

Storage: Store at ambient temperature

Loperamide

Polfa Warszawa S.A.

Polfa Warszawa S.A.,
street Karolkowa 22/24,
01-207 Warszawa,
EN

Treatment of diarrhea with Loperamide WZF is only symptomatic. In each case in which it is possible to determine the etiology, when it is justified (or indicated), causal treatment should be applied. The most important thing in acute diarrhea is to prevent or restore lost fluids and electrolytes. This is especially important for children, debilitated patients and elderly people with severe diarrhea. It is recommended to administer adequate amounts of fluids and electrolytes when using this product. Because long-term diarrhea may be a symptom of more serious diseases, loperamide should not be used long-term until the cause of the diarrhea is determined. If, in the treatment of acute diarrhea, no improvement in the patient's clinical condition is observed within 48 hours,the administration of Loperamide WZF should be discontinued and the patient should consult a doctor. In AIDS patients treated with loperamide for diarrhea, the product should be discontinued at the first sign of abdominal distension. There are isolated reports of constipation with an increased risk of toxic megacolon when loperamide is used in AIDS patients with infectious colitis caused by both bacteria and viruses. Despite the lack of data on the pharmacokinetics of the product in patients with hepatic impairment, Loperamide WZF should be used with caution in this group of patients due to decreased metabolism associated with the first-pass effect through the liver. In patients with impaired liver function, a relative overdose of the drug may occur, leading to toxic effects on the central nervous system. If a patient is using this product to control episodes of diarrhea associated with a diagnosis of irritable bowel syndrome and there is no clinical improvement within 48 hours, the product should be discontinued and a physician should be consulted. Patients should also consult a doctor if symptoms change or if recurrent episodes of diarrhea last longer than two weeks. Cases of cardiac events have been reported in association with overdose, including prolongation of the QT interval and QRS duration, as well as torsade de pointes. In some cases, death occurred. Do not exceed the recommended dose or duration of treatment. An overdose may lead to the manifestation of existing Brugada syndrome. Due to the lactose content, the product should not be used in patients with rare hereditary problems of galactose intolerance, the lactase deficiency or glucose-galactose malabsorption.